H-Nva-OMe hydrochloride - Names and Identifiers
H-Nva-OMe hydrochloride - Physico-chemical Properties
Molecular Formula | C6H14ClNO2
|
Molar Mass | 167.63 |
Boling Point | 197.5°C at 760 mmHg |
Flash Point | 73.2°C |
Vapor Presure | 0.319mmHg at 25°C |
Appearance | Solid |
Color | Off-white to white |
Storage Condition | Inert atmosphere,Room Temperature |
H-Nva-OMe hydrochloride - Risk and Safety
H-Nva-OMe hydrochloride - Introduction
H-Nva-OMe . HCl (H-Nva-OMe . HCl) is a compound consisting of L-norvaline methyl ester (Nva-OMe) and hydrochloric acid (HCl).
Nature:
1. Appearance: H-Nva-OMe . HCl is a white to light yellow crystalline powder.
2. Solubility: It is soluble in water, but has low solubility in organic solvents.
Use:
H-Nva-OMe . HCl is widely used in organic synthesis. It can be used as a valine protecting group in the synthesis of highly active peptides to avoid side reactions and improve yield. In addition, it can also be used in drug development, protein synthesis and modification.
Preparation Method:
The preparation of H-Nva-OMe . HCl is usually carried out by the following steps:
1. Dissolve L-norvaline methyl ester in an appropriate solvent.
2. Slowly add concentrated hydrochloric acid dropwise to the solution and keep the reaction temperature suitable.
3. Stir the reaction mixture until a precipitate forms.
4. Centrifuge, wash and dry the precipitate to obtain H-Nva-OMe. HCl.
Safety Information:
1. H-Nva-OMe . HCl should be stored in a dry, well-ventilated place, away from fire and oxidant.
2. Use appropriate personal protective equipment, including chemical protective glasses, protective gloves and laboratory coats.
3. Avoid contact with skin, eyes and respiratory tract. If exposed, rinse immediately with plenty of water and seek medical attention.
4. When using and handling H-Nva-OMe. HCl, please use appropriate operating procedures to avoid exposure or accidents.
Please note that when conducting any chemical experiments or using chemical substances, make sure to follow the correct laboratory safety regulations, and carefully read and follow the safety technical instructions of relevant chemicals.
Last Update:2024-04-09 15:17:58